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用高效液相色谱测定３４例反复呼吸道感染患儿血清β－胡萝卜素、维生素Ａ（ＶｉｔＡ）与维生素Ｅ（ＶｉｔＥ）的含量。同时测定了血清免疫球蛋白水平。结果显示：①患儿组β－胡萝卜素及ＶｉｔＡ含量明显低于对照组（Ｐ＜０．０５及Ｐ＜０．０１），两组ＶｉｔＥ则无显著性差异。②亚临床型ＶｉｔＡ缺乏在患儿组为２４例（２４／３４例，７０．５％），对照组中为１３例（１３／４０例，３２．５％），有显著性差异（Ｘ２＝１０．６６，Ｐ＜０．００５）。临床型ＶｉｔＡ缺乏则在两组均未见到。③患儿组ＩｇＡ水平与β－胡萝卜素、ＶｉｔＡ的相关系数ｒ分别为０．３５４（ｔ＝２．２５，Ｐ＜０．０５）及０．３２２（ｔ＝１．９２４，Ｐ＜０．０５），均显著相关。ＩｇＧ及ＩｇＭ则与两种维生素之间均无显著相关。提示，β－胡萝卜素和ＶｉｔＡ缺乏时ＩｇＡ水平降低，与呼吸道易受感染可能有关。防治反复呼吸道感染时宜服用β－胡萝卜素及／或ＶｉｔＡ，以前者防治效果为优。
The contents of β-carotene, VitA and VitE in 34 children with recurrent respiratory tract infection were measured by HPLC. Simultaneous determination of serum immunoglobulin levels. The results showed that: ①β-carotene and VitA levels in children were significantly lower than those in the control group (P <0.05 and P <0.01), VitE in both groups showed no significant difference. ② The subclinical VitA deficiency was 24 (24/34 cases, 70.5%) in the pediatric group and 13 (13/40 cases, 32.5%) in the control group, with significant difference (X2 = 10.66, P <0.005). Clinical vitamin A deficiency was not seen in either group. ③ The correlation coefficient r of IgA level with β-carotene and VitA in children was 0.354 (t = 2.25, P <0.05) and 0.322 (t = 1.924, P <0.05). 05), were significantly related. There was no significant correlation between IgG and IgM and both vitamins. Tip, β-carotene and VitA lack of IgA levels, and respiratory tract infection may be related. Prevention and treatment of recurrent respiratory tract infection should take beta-carotene and / or VitA, the former control effect is excellent.