药品不良反应监察系列问答２５──性别对不良反应的发生有何影响？动物实验证明，给予同一剂量巴比妥时，雌鼠的睡眠时间比雄鼠长；氯仿能导致正常雄鼠出现肝损害但阉割雄鼠不受影响。临床研究表明，妇女比男子容易发生不良反应，如保太松引致妇女粒细胞缺乏症比男子高３... Q & A of Drug Adverse Drug Reaction Series Q: What is the influence of gender on the occurrence of adverse reactions? Animal experiments show that, given the same dose of barbiturates, female rats sleep longer than male rats; chloroform can cause liver damage in normal male rats but castration male rats are not affected. Clinical studies have shown that women are more prone to adverse reactions than men, such as Paul caused by loosely induced agranulocytosis than men 3 ...