目的分析1999~2008年桂林市狂犬病流行特征,探讨狂犬病流行相关因素,为狂犬病预防控制策略和措施的制定提供依据。方法收集1999~2008年桂林市狂犬病疫情资料、个案调查资料和专题调查资料,用Excel2003进行统计。结果10年间,桂林市共报告狂犬病400例,年平均发病率0.82/10万。97.25%的病例发生在农村地区,0~9岁和40~59岁组分别是发病的两个年龄高峰。85.89%的伤人动物为家养动物,93.17%的伤人动物未被处死后深埋或焚烧。99.55%的病例暴露后未接受正确处置。结论十年来的防控工作虽取得一定成效,但桂林市狂犬病形势依然严峻,应提高全社会对犬患的足够认识,实施政府综合干预措施,坚决落实犬只捕杀办法,并从整顿和改善医疗环境入手,促进人群接受暴露后正确处置。 Objective To analyze the epidemiological characteristics of rabies in Guilin from 1999 to 2008, and to explore the related factors of rabies epidemic in order to provide basis for the formulation of preventive and control strategies and measures for rabies. Methods The rabies epidemic data, case investigation data and special survey data from 1999 to 2008 in Guilin were collected and statistically analyzed with Excel2003. Results In 10 years, a total of 400 cases of rabies were reported in Guilin, with an average annual incidence of 0.82 / 100000. 97.25% of the cases occurred in rural areas, 0 to 9 years old and 40 to 59 years old were the incidence of the two age peaks. 85.89% of domestic animals were domestic animals and 93.17% of them were buried or incinerated without being executed. 99.55% of cases did not receive proper treatment after exposure. Conclusion Although the prevention and control work over the past decade has achieved some success, the situation of rabies in Guilin is still grim. We should raise enough awareness of dogs in the whole society, implement comprehensive government interventions, resolutely implement ways of killing dogs, and rectify and improve medical treatment Environmental start, to promote proper exposure after exposure to the crowd.