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为了解新疆维吾尔自治区部分县市健康人群麻疹抗体水平,在1997 年10 月至1998 年10 月间,采用多阶段抽样方法,对哈密地区和巴音部郭楞蒙自治洲博湖县的617 名0~39 岁的健康人群进行了调查。结果显示:博湖县和哈密地区麻疹抗体阳性率分别为92.9% 和89.3% ,抗体滴度≥1∶800 的比例分别为64.6% 和58.9% ,但抗体几何平均滴度(GMT)低于1990 年全疆平均水平。这可能与近几年基础免疫和加强免疫工作质量有下降、麻疹疫苗免疫持久性下降有关。<1 岁组和1 岁组麻疹抗体水平有显著性差异(χ2= 9.96 ,P<0 .05);而1~9 岁各年龄组间抗体水平无显著性差异。人群抗体滴度≥1∶800 的比例为61.8% 。根据此次调查可以预测两地区易感人群主要为0~15 岁儿童,应有针对性的制定有效的免疫对策,结合流行病学资料,及时发现并保护易感人群,达到控制麻疹的目的。
To understand the level of measles antibody in healthy population in some counties and cities in Xinjiang Uygur Autonomous Region, from October 1997 to October 1998, 617 0 to 39-year-old healthy population surveyed. The results showed that the positive rates of measles antibody in Bohu and Hami areas were 92.9% and 89.3% respectively, and the antibody titers ≥1: 800 were 64.6% and 58.9% respectively, but the geometric mean of antibody The titer (GMT) is lower than the average of Xinjiang in 1990. This may be related to the drop in the quality of basic immunization and booster immunization in recent years and the persistent decline in immunity to measles vaccine. There was a significant difference in measles antibody level between the 1-year-old group and the 1-year-old group (χ2 = 9.96, P <0 .05). There was no significant difference in antibody levels among all age groups from 1 to 9 years old. The proportion of population antibody titers ≥1: 800 was 61.8%. According to the survey, predominantly 0 to 15-year-old children in both areas can be predicted. Effective immunization measures should be formulated in a targeted manner. Epidemiological data should be used to detect and protect susceptible people in time so as to control measles.