Zn、Cu、Se均是人体的必需微量元素,如缺乏可引起免疫器官发育障碍,并影响机体的体液免疫、细胞免疫、补体系统以及机体的天然防御系统。Zn、Cu、Se等缺乏引起的免疫系统损伤是可复性的,通过补充适量的缺乏元素,可使机体的免疫功能恢复。摄入或补充过量的Zn、Cu、Se也可使免疫功能受损,表现在淋巴细胞对有丝分裂原的反应、NK细胞活性和抗体产生量下降等。Zn、Cu、Se影响免疫功能的机理目前正在继续进行探讨。 Zn, Cu and Se are essential microelements of the human body. For example, they lack the natural defense system that can cause the development of immune organs and affect the body’s humoral immunity, cellular immunity, complement system and body. Zn, Cu, Se and other deficiencies caused by immune system damage is refolding, by adding the appropriate amount of lack of elements, can make the body’s immune function recovery. Excessive ingestion or replenishment of Zn, Cu, Se also impairs immune function, manifested in response of lymphocytes to mitogens, NK cell activity and antibody production decline. The mechanisms by which Zn, Cu and Se affect immune function are currently under discussion.