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目的探讨N末端脑钠肽前体在不典型心力衰竭中的诊断价值。方法选取2011年1月份至2012年2月份我院心内科57例不典型心力衰竭患者为研究对象,设为观察组;另选择同时期在心内科住院的非心力衰竭患者55例为对照组。分别检查两组患者的N末端脑钠肽前体值,同时比较血浆N末端脑钠肽前体在各级心功能心衰患者中的检测值。结果实验组平均N末端脑钠肽前体值为(324.3±35.8)pg/ml,明显高于对照组患者;实验组患者中心功能分级大于二级的患者平均N末端脑钠肽前体值为(458.5±42.1)pg/ml,明显高于心功能小于等于二级的患者。两组差异具有统计学上的意义,P<0.05。结论N末端脑钠肽前体值在不典型心力衰竭患者当中明显升高,同时心功能分级越高N末端脑钠肽前体值越大。
Objective To investigate the diagnostic value of N-terminal pro brain natriuretic peptide in atypical heart failure. Methods From January 2011 to February 2012, 57 cases of atypical heart failure in our department of cardiology were selected as observation group and 55 cases of non-heart failure patients who were hospitalized in cardiology department during the same period were selected as control group. The levels of N-terminal pro-brain natriuretic peptide in the two groups were examined, and the plasma N-terminal pro-brain natriuretic peptide was compared in all the patients with cardiac dysfunction. Results The mean value of N-terminal pro-brain natriuretic peptide in the experimental group was (324.3 ± 35.8) pg / ml, which was significantly higher than that in the control group. The average N-terminal pro-brain natriuretic peptide in the experimental group was (458.5 ± 42.1) pg / ml, which was significantly higher than that in patients with cardiac function less than or equal to two levels. The difference between the two groups was statistically significant, P <0.05. Conclusions The N-terminal pro-brain natriuretic peptide is significantly elevated in patients with atypical heart failure, and the higher the N-terminal pro-brain natriuretic peptide level, the higher the cardiac function grade.