论文部分内容阅读
本文研究了298例乙型肝炎表面抗原(称 HBsAg)阳性者,其中76例诊断为慢性活动性肝炎,17例诊断为慢性迁延性肝炎,205例为无症状 HBsAg 携带者。研究结果表明,HBsAg 滴度与 HBeAg(乙型肝炎 e 抗原)及肝功能三者之间存在比较密切的关系,并且与慢性肝炎的发生率相关。肝功能异常率随着HBsAg 滴度的升高而明显增加(P<0.005),而且慢性肝炎患者的 HBeAg 阳性率显著高于无症状 HBsAg 携带者(P<0.005)。结果启示,检测 HBeAg和 HBsAg 滴度,肝功能试验对判断乙型肝炎感染率、传染性、早期诊断、病情转归、肝脏损害程度以及开展防治工作等方面均有现实指导意义。
In this paper, 298 cases of hepatitis B surface antigen (HBsAg) positive, of which 76 cases were diagnosed as chronic active hepatitis, 17 cases of chronic persistent hepatitis and 205 cases of asymptomatic HBsAg carriers. The results show that there is a close relationship between HBsAg titer and HBeAg (hepatitis B e antigen) and liver function, and is related to the incidence of chronic hepatitis. The abnormal rate of liver function increased with the increase of HBsAg titer (P <0.005), and the HBeAg positive rate of patients with chronic hepatitis was significantly higher than that of asymptomatic HBsAg carriers (P <0.005). The results suggest that the detection of HBeAg and HBsAg titers, liver function tests to judge the hepatitis B infection rate, infectious, early diagnosis, the prognosis of the disease, the degree of liver damage and carry out prevention and treatment work have practical significance.