本实验将胎龄为15d的胎鼠大脑皮质移植到中年Wistar大鼠大脑皮质3,1,2区内。移植物成活120d时取材,超薄切片,电镜观察。移植物—宿主脑组织交界区内有形态变异的神经元。Ⅰ类,发育迟缓神经元,胞体呈梭形,胞质内缺乏线粒体。Ⅱ类,分化异常神经元,胞体可发出数条类似正常的“轴突”。Ⅲ类,变性坏死神经元。本文并对上述现象出现的原因进行了探讨。 In this study, fetal rat cerebral cortex with gestational age of 15 days was implanted into 3, 1, and 2 regions of cerebral cortex of middle-aged Wistar rats. Transplant survival 120d drawn, ultra-thin sections, electron microscopy. Graft - host brain tissue junctional area with morphological changes in neurons. Ⅰ type, stunted neurons, spindle-shaped cell bodies, the lack of mitochondria within the cytoplasm. Class II, differentiated neurons, cell body can issue several similar normal “axons.” Class Ⅲ, degenerative and necrotic neurons. This article also discusses the reasons for the above phenomenon.