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以前曾发表过某些间歇接受利福平的病人出现肝肾功能衰竭的报告,但尚未证实有利福平依赖抗体.作者报告一例给利福平时并发肝肾功能衰竭的病例并证实有利福平依赖抗体。病者男性,21岁,患活动性肺结核,每天给予利福平1200mg,雷米封500mg及乙胺丁醇1000mg。治疗3天后发生严重(口恶)心呕吐而停利福平代之以每天链霉素1g。3月后停用链霉素,每周给二次利福平,每次900mg。此疗法持续到病人来就诊前15天,没有任何理由停用利福平10天。而后服利福平900mg 2小
Previously published reports of liver and renal failure in some intermittent patients receiving rifampicin but no evidence of rifampicin-dependent antibodies The authors report a case of rifampin complicated with hepatorenal failure and confirmed a favorable dependence of rifampicin antibody. Male, 21 years old with active tuberculosis, was given rifampicin 1200 mg daily, 500 mg Remy pack and 1000 mg ethambutol. Serious (mouth evil) vomiting occurred 3 days after treatment and stopped taking rifampicin daily with streptomycin 1g. 3 months after the suspension of streptomycin, rifampin twice a week, each 900mg. The therapy lasted 15 days before the patient came to the clinic and there was no reason to stop rifampicin for 10 days. Rifampicin and then take 900mg 2 small