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目的:对乙型肝炎患者甲状腺功能指标检测结果进行分析,探讨其临床意义。方法:选取于2012年12月-2013年12月在我院接受治疗的乙型肝炎患者116例为研究对象,同时选取同期在我院接受体检的健康人50例为对照组,对上述选取对象取样血清中的促甲状腺激素(TSH)、游离T3(FT3)、游离T4(FT4)、总T3(TT3)、总T4(TT4)、反式T3(rT3)等甲状腺功能指标水平进行检测,对检测结果进行分析。结果:乙型肝炎组较对照组对比,其TSH、FT3、FT4、TT3、TT4等检测水平明显下降,rT3水平明显上升,两组间上述指标对比差异有统计学意义(P<0.05);而在乙型肝炎组患者中,随着肝炎病况的加重,TSH、FT3、FT4、TT3、TT4等检测水平明显下降,rT3水平上升。结论:乙型肝炎患者随着其病情的发生和炎症的加重,其甲状腺功能也随之会受到影响,两者之间存在明显的相关性,因而临床上可采取检测血清中甲状腺功能指标水平的方式来判断慢性乙肝患者病情的发展及预后情况。
Objective: To analyze the results of thyroid function test in patients with hepatitis B and to explore its clinical significance. Methods: One hundred and sixty-six patients with hepatitis B treated in our hospital from December 2012 to December 2013 were enrolled in this study. Fifty healthy subjects undergoing physical examinations in our hospital were selected as the control group. Serum levels of thyroid stimulating hormone (TSH), free T3 (FT3), free T4 (FT4), total T3 (TT3), total T4 (TT4), and trans T3 (rT3) Test results for analysis. Results: Compared with the control group, the levels of TSH, FT3, FT4, TT3 and TT4 in the hepatitis B group were significantly decreased, while the levels of rT3 in the hepatitis B group were significantly increased. There was significant difference between the two groups (P <0.05) In the hepatitis B group, the detection level of TSH, FT3, FT4, TT3, TT4 and so on increased significantly with the aggravation of hepatitis. Conclusion: With the occurrence of hepatitis B patients and the aggravation of inflammation, the thyroid function will also be affected, there is a clear correlation between the two, so clinically taken to detect the level of serum thyroid function indicators Way to determine the development of chronic hepatitis B patients and prognosis.