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用清醒动物研究咪唑安定(Midazolam,M)对氯胺酮(Ketamin,K)药理效应的影响,探讨两药合用后的优缺点,为临床麻醉提供药理学依据。材料与方法 昆明种雌性小鼠(n=10)、白色家兔(n=8),均按分层随机设计分组。催眠以翻正反射消失率(入睡率)和持续时间(睡眠时间)为指标。镇痛用热板?
The effects of Midazolam on the pharmacological effects of Ketamin (K) were studied in conscious animals to explore the advantages and disadvantages of the combination of the two drugs and provide a pharmacological basis for clinical anesthesia. MATERIALS AND METHODS Kunming female mice (n = 10) and white rabbits (n = 8) were randomly divided into groups according to their stratification. Hypnosis to the right reflection loss (falling asleep) and duration (sleep time) as an indicator. Analgesic with hot plate?