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应用器官培养(Organ culture)研究气管粘膜上皮的癌变是肺癌实验研究的一种较好手段。可以应用这种方法研究肺癌的病因、癌变机理以及探索予防措施。用化学性致癌物质诱发离体器官培养的气管粘膜上皮细胞的癌变,制造实验性肺癌模型是上述一系列实验研究的基础。作者应用20—甲基胆蒽作用于离体培养的大鼠气管粘膜,发现
Organ culture The study of the carcinogenesis of tracheal mucosal epithelium is a good method for the experimental study of lung cancer. This method can be used to study the etiology of lung cancer, cancer mechanisms and to explore preventive measures. The carcinogenesis of tracheal mucosal epithelial cells cultured in isolated organs induced by chemical carcinogens is the basis of a series of experimental studies described above. The authors applied 20-methylcholene induced rat tracheal mucosa cultured and found