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目的分析经皮冠状动脉介入治疗(PCI)伴冠心病(CHD)家族史阳性患者临床及冠脉病变特点。方法该院2006年12月-2014年6月13 800例行PCI患者中选取伴CHD家族史阳性者1300例,随机抽取无CHD家族史PCI患者1000例作为阴性组。对CHD家族史阳性组和阴性组临床及冠脉病变特点进行比较。结果在13 800例PCI患者中发现CHD家族史阳性者1300例,占PCI总数的9.4%。阳性组患者的BMI以及糖尿病、高血压病、左主干病变和单/双/三支病变发生率与阴性组无显著差异(P>0.05),发病年龄和吸烟患者发生率显著低于阴性组,而男性、高脂血症、AMI和开口病变、CTO发生率均显著大于阴性组,差异均有统计学意义(P<0.05)。结论 PCI患者中CHD家族史阳性率为9.4%,CHD家族史阳性患者中男性、高脂血症、AMI和复杂冠脉病变多于无家族史者。
Objective To analyze the clinical features and coronary artery lesions in patients with positive family history of coronary artery disease (PCI) and coronary heart disease (CHD). Methods The hospital from December 2006 to June 2014 13 800 cases of PCI patients selected with CHD family history of positive in 1300 cases were randomly selected 1000 cases without CHD family history of PCI patients as a negative group. The clinical and coronary characteristics of CHD family history positive group and negative group were compared. Results Of the 13 800 PCI patients, 1300 were found to have a positive family history of CHD, accounting for 9.4% of the total number of PCI. The positive rate of BMI and diabetes, hypertension, left main disease and single / double / triple lesions were not significantly different from those in the negative group (P> 0.05). The incidence of disease and smoking were significantly lower in the positive group than in the negative group, However, the incidence of male hyperlipidemia, AMI, open lesions and CTO were significantly higher than those in the negative group (P <0.05). Conclusions The positive rate of CHD family history in PCI patients is 9.4%. There is more male, hyperlipidemia, AMI and complicated coronary artery disease than those without family history in CHD family history positive patients.