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妊娠期血栓病（ＴＤＰ）已成为孕妇围产期死亡率和病率的主要原因。妊娠人群发生率为０．０５％ ～０．３％ ，血栓性疾病高危者ＴＤＰ的危险性增至７．５％ ～１２％ 。妊娠期凝血系统变化是ＴＤＰ的主要原因。Ｃ蛋白、Ｓ蛋白及抗凝血因子Ⅲ缺乏致ＴＤＰ的危险性升高，抗磷脂抗体也与ＴＤＰ有关。血流阻抗图（ＩＰＧ）及超声波检查可用于筛选和诊断ＴＤＰ，ＭＲＩ和静脉造影有助于ＴＤＰ的确诊。对高危ＴＤＰ者应采取预防措施。肝素是防治ＴＤＰ的主要抗凝剂，妊娠期使用较为安全。
Pregnancy thrombosis (TDP) has become the leading cause of perinatal mortality and morbidity in pregnant women. Pregnancy incidence of 0.05% to 0.3%, the risk of thrombotic disease in high-risk TDP increased to 7.5% to 12%. Changes in pregnancy coagulation system is the main reason for TDP. C protein, S protein and anti-coagulation factor Ⅲ-induced increased risk of TDP, anti-phospholipid antibodies and TDP. Blood flow impedance (IPG) and sonography can be used to screen and diagnose TDP. MRI and venography contribute to the diagnosis of TDP. For high-risk TDP should take precautionary measures. Heparin is the main anticoagulant for the prevention and treatment of TDP, the use of safer pregnancy is more secure.