本文对生物碱抑制人精子的代谢和活动能力作了试验。其中最有效的是氯喹,有效浓度为3.6×10~(-5)M,奎宁、阿的平的有效浓度为5×10~(-4)M,而吐根碱为3.6×10~(-3)M浓度才能抑制精子的活动。对于吐根碱的详细研究表明:抑制精子所需的时间与药物浓度成反比,与精子浓度成正比,这种抑制是不可逆的。作者对这类药物对于精子细胞的作用机理也进行了探讨。 In this paper, alkaloid inhibition of human sperm metabolism and activity were tested. The most effective one is chloroquine, the effective concentration is 3.6 × 10 ~ (-5) M, the effective concentration of quinine and azepin is 5 × 10 ~ (-4) M, and the emetine is 3.6 × 10 ~ ( -3) M concentration can inhibit sperm activity. A detailed study of emetine shows that the time required to suppress sperm is inversely proportional to the concentration of the drug, which is inversely proportional to the concentration of sperm. The authors also discussed the mechanism of action of these drugs on sperm cells.