硝苯地平 (ｎｉｆｅｄｉｐｉｎｅ ,ＮＦ ,心痛定 ) ,是第一代二氢吡啶类中选择性钙拮抗药。过去常用于心血管疾病的治疗。近几年来 ,临床治疗中还发现ＮＦ是治疗贲门失驰缓症的理想药物之一。1　硝苯地平的药理作用Ｃａ2 + 作为细胞内信息分子即第二信使 ,在心肌和平滑肌的兴奋 Nifedipine (nifedipine, NF, nifedipine), is the first generation of dihydropyridine selective calcium antagonist. Used to treat cardiovascular disease. In recent years, clinical treatment also found that NF is one of the ideal drugs for the treatment of cardia deaceity. 1 pharmacological effects of nifedipine Ca2 + as intracellular information molecules that the second messenger, in the myocardium and smooth muscle excitement