论文部分内容阅读
目的探讨老年慢性阻塞性肺疾病(COPD)患者急性加重期血浆D-二聚体(D-D)、凝血酶-抗凝血酶复合物(TAT)、和纤溶酶-抗纤溶酶复合物(PAP)含量的检测方法及意义。方法选取58例老年COPD急性加重期患者为研究对象,并选取50例老年COPD缓解期患者为对照组,检测两组患者血浆D-D、TAT和PAP含量。结果与缓解期患者相比,急性加重期患者血浆D-D、TAT和PAP含量明显较高,两组对比差异有统计学意义(P<0.05)。结论血浆D-D、TAT、和PAP含量在老年COPD患者急性加重期显著增高,及早检测三项指标含量有助于老年COPD患者急性加重期早期诊断。
Objective To investigate the relationship between plasma D-dimer (DD), thrombin-antithrombin complex (TAT) and plasmin-antiplasmin complex in elderly patients with chronic obstructive pulmonary disease (COPD) PAP) content of the detection methods and significance. Methods Fifty-eight elderly patients with acute exacerbation of COPD were enrolled in this study. Fifty elderly patients with COPD during remission were selected as the control group. The levels of plasma D-D, TAT and PAP in the two groups were detected. Results Compared with patients in remission stage, the levels of plasma D-D, TAT and PAP were significantly higher in patients with acute exacerbation, the difference was statistically significant (P <0.05). Conclusions Plasma D-D, TAT, and PAP levels are significantly increased in elderly patients with COPD at acute exacerbation stage. Early detection of three indicators may contribute to the early diagnosis of acute exacerbation in elderly COPD patients.