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[目的]观察口服苁蓉通便口服液联合莫沙必利对化疗所致便秘的疗效。[方法]采用随机对照的方法,化疗后便秘患者68例,随机分为两组,A组给予口服莫沙比利5mg/次,3次/d,苁蓉通便口服液10ml/次,2次/d;B组单用莫沙比利,剂量同A组;疗程均为1周。记录患者服药前后大便间隔天数、大便性状的改变、排便困难程度改变及不良反应。[结果]治疗1周后,两组总有效率分别为88.2%和61.8%,疗效差异有统计学意义(P<0.05)。[结论]苁蓉通便口服液联合莫沙必利治疗化疗所致的便秘安全,使用方便,具有较好的疗效。
[Objective] To observe the curative effect of oral Cistanche and Tongbai oral liquid and Mosapride on constipation caused by chemotherapy. [Methods] 68 patients with constipation after chemotherapy were randomly divided into two groups. The patients in group A received oral administration of mosapride 5mg / time 3 times daily, Cistanche Buchi oral liquid 10ml / time, Times / d; group B alone mosapride, the same dose with the A group; course of treatment for 1 week. Record patients before and after taking stool interval days, stool changes, changes in the degree of defecation and adverse reactions. [Results] After one week of treatment, the total effective rates of the two groups were 88.2% and 61.8%, respectively, with statistically significant differences (P <0.05). [Conclusion] Cistanche constipation oral combined with mosapride in the treatment of constipation caused by chemotherapy is safe, easy to use and has good curative effect.