流脑流行群的带菌者,是流脑的主要传染源。在流脑流行地区,人群中都有流脑流行群带菌率的显著上升;因而在流脑流行区、特别是爆发点,消除或减少带菌者,对保护易感人群及控制疫情而言,有重要意义。六十年代以前,国内外应用磺胺类作消菌预防药,对控制流行取得显著效果,但随着抗磺胺菌株的增加,六十年代以后逐渐失 The carrier of meningococcal epidemic group, is the main source of infection of meningitis. In endemic areas of meningitis, there is a marked increase in the prevalence of meningococcal endemic groups in the population; thus eliminating or reducing carriers in the endemic areas of meningitis, especially at the outbreak, for the protection of susceptible populations and the control of outbreaks, there are Significance. Sixty years ago, the domestic and international application of sulfonamides as antimicrobial prophylactic drugs, control of the epidemic achieved remarkable results, but with the increase of anti-sulfa strains, gradually lost after the 1960s