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目的探讨临床药敏试验对医院感染控制的指导意义。方法采用K-B纸片扩散法对1055株临床致病菌进行了抗生素敏感性测定。结果总耐药率最低的是丁胺卡那(8%)、亚胺培南(8.4%)和头孢他啶(18.5%)。其它头孢类抗生素一般在50%左右。氨苄西林及哌拉西林的耐药率最高。耐药菌株百分率较高的菌种有:嗜麦芽寡养单胞菌、屎肠球菌、铜绿假单胞菌及耐苯唑西林的葡萄球菌。结论提出了“耐药指数”的概念,试图用它表示某种被试菌的全部菌株对所试抗生素总的耐药程度
Objective To explore the clinical significance of drug susceptibility testing in hospital infection control. Methods The antibiotic sensitivity of 1055 clinical pathogenic bacteria was determined by K-B disk diffusion method. Results The lowest rates of total resistance were amikacin (8%), imipenem (8.4%) and ceftazidime (18.5%). Other cephalosporins generally about 50%. Ampicillin and piperacillin have the highest rates of resistance. Strain resistant strains higher strains: Stenotrophomonas maltophilia, Enterococcus faecium, Pseudomonas aeruginosa and oxacillin resistant staphylococcus. Conclusion The concept of “resistance index” was put forward and it was attempted to use it to indicate that the total drug resistance of all the tested strains to the tested antibiotics