结缔组织病的病因未明,但多主张属自身免疫性疾病.其治疗在很大程度上取决于在发病机理中起重要作用的淋巴细胞属于哪一类,属于B细胞采用能抑制抗体产生的药物,属T细胞用破坏反应性过高的效应T细胞或刺激功能不足的抑制性T细胞的药物治疗.根据此基础,治疗结缔组织病的药物可从以下几方面加以选择:1.抑制巨噬细胞对抗原的摄取及处理,如糖皮质激素.2.于免疫反应的增殖期阻止免疫活性细胞的分裂与增殖如烃化剂、抗代谢药.3.减弱自 The etiology of connective tissue disease is unknown, but more advocates are autoimmune diseases, the treatment depends largely on which lymphocytes play an important role in the pathogenesis of which belongs to B cells with drugs that inhibit antibody production , Are T cells treated with drugs that destroy effector T cells that are hyperactive or that stimulate underreacting suppressive T cells.On the basis of this, drugs for treating connective tissue disease can be selected from the following aspects: 1. Inhibition of macrophages Cell uptake and treatment of antigens, such as glucocorticoids .2 in the immune response during the proliferation of immune cells to prevent cell division and proliferation, such as alkylating agents, antimetabolites .3 weakened since