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目的观察双联抗血小板联合丁苯酞注射液治疗急性脑梗死(ACI)的临床疗效。方法选取2016年莱芜钢铁集团有限公司医院收治的ACI患者120例,根据治疗方法分为对照组和观察组,每组60例。在常规治疗基础上,对照组患者给予双联抗血小板治疗,观察组患者给予双联抗血小板联合丁苯酞注射液治疗;两组患者均连续治疗14 d。比较两组患者临床疗效及治疗后3 d、7 d、14 d美国国立卫生研究院卒中量表(NIHSS)评分。结果观察组患者临床疗效优于对照组(P<0.05)。治疗后3 d两组患者NIHSS评分比较,差异无统计学意义(P>0.05);治疗后7、14 d观察组患者NIHSS评分低于对照组(P<0.05)。结论双联抗血小板联合丁苯酞注射液治疗ACI的临床疗效确切,可有效改善患者神经功能。
Objective To observe the clinical efficacy of dual antiplatelet combined with butylphthalide in the treatment of acute cerebral infarction (ACI). Methods 120 cases of ACI patients admitted to the hospital of Laiwu Iron and Steel Group Co., Ltd. in 2016 were divided into control group and observation group according to the treatment method, 60 cases in each group. On the basis of routine treatment, patients in the control group were treated with dual antiplatelet therapy and patients in the observation group were treated with dual antiplatelet plus butylphthalide. Patients in both groups were treated for 14 consecutive days. The clinical efficacy of the two groups were compared and the NIH Stroke Scale (NIHSS) score was assessed at 3 d, 7 d and 14 d after treatment. Results The clinical efficacy of the observation group was better than that of the control group (P <0.05). There was no significant difference in NIHSS score between the two groups on the 3rd day after treatment (P> 0.05). NIHSS scores in the observation group were lower than those in the control group on the 7th and 14th day after treatment (P <0.05). Conclusions Double antiplatelet combined with butylphthalide injection for the treatment of ACI has definite curative effect and can effectively improve the neurological function.