安体舒通为储钾排钠利尿剂,与其它利尿药配伍,可减少利尿引起的低钾血症。由于其抗醛固酮作用,肝性腹水时使用效果更佳。故临床上广泛使用,较少报道其毒副作用。现将1例肝性腹水患者,使用安体舒通后出现皮疹、头痛、记忆力和计算力减退等,报道如下:韩某,男性,25岁。因恶心,呕吐伴皮肤、巩膜黄染半月,于1986年1月4日入院。患者有慢性肝炎病史4年。查体慢性肝炎病容、皮肤、巩膜重度黄染,颈部可见蜘蛛痣,腹部膨隆,肝脾未触及,腹水征(-)。化验检查:血白细胞3,800,血小板70,000,胆红质14mg,谷丙转氨酶440u,麝香草酚浊度试验14u,麝香草酚絮状试验(+++),白蛋白与 Spironolactone is a potassium-releasing sodium diuretic that is compatible with other diuretics to reduce the hypokalemia caused by diuresis. Because of its anti-aldosterone effect, the use of hepatic ascites better. It is widely used clinically, less reported side effects. Now a case of liver ascites patients, the use of spironolactone rash, headache, memory loss and calculation, etc., are reported as follows: Han, male, 25 years old. Due to nausea, vomiting with the skin, scleral buckthorn half moon, January 4, 1986 admission. Patients have a history of chronic hepatitis 4 years. Physical examination of chronic hepatitis disease, skin, sclera severe yellow dye, visible spider nevus neck, bulging abdomen, liver and spleen not touched, signs of ascites (-). Laboratory tests: white blood cells 3,800, platelets 70,000, 14mg of bilirubin, alanine aminotransferase 440u, thymol turbidity test 14u, thymol flocculus test (+++), albumin and