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目的观察双水平气道正压通气(BIPAP)治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停综合征(OS)的临床疗效。方法选取2012年1月—2013年1月我院收治的OS患者100例,按照治疗方法不同将其分为A组和B组,各50例。A组进行BIPAP治疗,B组进行持续气道正压通气(CPAP)治疗,均治疗7 d。比较两组治疗前后动脉血气指标、多导睡眠图(PSG)指标、病死率及不良反应发生情况。结果治疗后,A组pH高于B组,病死率及不良反应发生率、PaCO2、呼吸暂停指数(AHI)、最长呼吸暂停时间均低于B组(P<0.05)。结论采用BIPAP治疗OS,能够显著降低患者病死率、减少不良反应发生率,有效改善患者呼吸情况,提高睡眠质量。
Objective To observe the clinical effect of bipolar positive airway pressure (BIPAP) on chronic obstructive pulmonary disease (COPD) complicated with obstructive sleep apnea syndrome (OSA). Methods 100 patients with OS in our hospital from January 2012 to January 2013 were divided into group A and group B according to the different treatment methods, 50 cases in each group. Group A received BIPAP treatment and Group B received continuous positive airway pressure (CPAP) treatment for 7 days. The arterial blood gas index, polysomnography (PSG) index, case fatality rate and incidence of adverse reactions were compared between the two groups before and after treatment. Results After treatment, the pH value of group A was higher than that of group B, and the mortality and incidence of adverse reactions, PaCO2, apnea index (AHI) and the longest apnea time were all lower than those in group B (P <0.05). Conclusion BIPAP treatment of OS can significantly reduce the mortality of patients, reduce the incidence of adverse reactions, effectively improve the respiratory status of patients and improve sleep quality.