急性白血病(急白)的感染与出血仍视为严重并发症,而口腔感染又成为突出的矛盾之一,有时作为细菌入侵的门户,可促使病情恶化,甚至危及生命。近十年来我室共收治急白643例,发生口腔严重感染23例(3.6%)。关于口腔严重感染的标准是:(1)除局部表现病变外,多伴有全身中毒症状;(2)口腔粘膜除广泛糜烂外,常发生多数溃疡;(3)发生局部蜂窝组织炎或合并败血症;(4)白细胞低下或异常升高;(5)常有致病菌培养阳性或个别白血病细胞浸润者。 Infection and bleeding of acute leukemia (acute white) are still regarded as serious complications, and oral infection has become one of the prominent contradictions, and sometimes as a gateway to bacterial invasion, can make the disease worse, and even life-threatening. In the past ten years, our hospital received a total of 643 cases of acute white and 23 cases (3.6%) of severe oral infections. Criteria for severe oral infections are: (1) in addition to the local performance of lesions, often accompanied by symptoms of systemic poisoning; (2) oral mucosa in addition to extensive erosion, the majority of ulcers often occur; (3) the occurrence of local cellulitis or sepsis ; (4) leukopenia or abnormal increase; (5) often pathogenic bacteria culture positive or individual leukemia cell infiltration.