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本期主要内容为全身性疾病与肾损害的探讨。胶原性疾病与肾损害一文介绍了系统性红斑狼疮(SLE)肾炎的组织分型,即肾小球基底膜增殖性SLE 肾炎,弥漫性增殖性SLE肾炎,局灶增殖性SLE 肾炎。膜性SLE 肾炎的诊断标准:①蛋白尿持续在1g/日以上,②尿常规检查有红细胞及各种管型,③肾功能进行性低下,④SLE 免疫学活性增高,抗核抗体、抗DNA 效价升高。血清补体检查,β_(1C)/β_(1A)球蛋白降低,血中免疫复合体升高。坏死性血管炎并发肾血管炎的发病率较高,其特点是易损
The main contents of this issue are systemic diseases and kidney damage. Collagen disease and renal damage article describes the systemic lupus erythematosus (SLE) nephritis tissue typing, namely, glomerular basement membrane proliferative SLE nephritis, diffuse proliferative SLE nephritis, focal proliferative SLE nephritis. Membranous SLE nephritis diagnostic criteria: ① proteinuria continued in 1g / day or more, ② urine routine examination of red blood cells and a variety of tubular, ③ renal dysfunction, ④ immunological activity of SLE increased anti-nuclear antibody, anti-DNA effect Price rises. Serum complement test, β_ (1C) / β_ (1A) globulin decreased blood immune complexes increased. The incidence of necrotizing vasculitis associated with renal vasculitis is higher, which is characterized by vulnerability