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目的探讨气管插管后气囊上液与呼吸机相关性肺炎(VAP)的相关性。方法对气管插管后确诊为VAP的患者,进行气囊上液、下呼吸道、口腔分泌物、胃液培养,并进行菌群对比,找出其相关性。结果下呼吸道分泌物与气囊上液的细菌成分为正相关,差异具有统计学意义,P<0.05。结论气囊上液是引起气管插管患者的呼吸机相关性肺炎的主要原因之一,气囊上液的细菌大多数来源于胃腔和口腔细菌的定植。
Objective To investigate the relationship between airway fluid and ventilator associated pneumonia (VAP) after tracheal intubation. Methods The patients with VAP after tracheal intubation were diagnosed as VAP. The upper airway, lower respiratory tract, oral secretions and gastric juice were collected and the flora was compared to find out their correlation. Results There was a positive correlation between the lower respiratory secretions and the bacterial components of the upper air bag, the difference was statistically significant (P <0.05). Conclusion Air sac is one of the main causes of ventilator-associated pneumonia in patients with endotracheal intubation. Most of the airborne bacteria in the air sac are derived from colonization of gastric cavity and oral bacteria.