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目的:探讨MRI平扫及DWI对低血糖脑病患者的临床诊断价值。方法:选取2013年6月~2015年6月间30例低血糖脑病患者为观察组,30例健康志愿者为对照组,均接受颅脑MRI平扫及DWI成像。分析低血糖脑病患者脑部病变特征,比较胼胝体压部及基底节区ADC值的差异。结果:病变部位以双侧额顶枕叶皮层及皮层下病变所占比例最高,呈T1WI略低信号,T2WI略高信号,T2 FLAIR高信号,DWI等或高信号。治疗前,低血糖脑病患者胼胝体压部及基底节区ADC值显著低于正常对照组,治疗后,低血糖脑病患者胼胝体压部及基底节区ADC值显著升高,与治疗前比较,差异具有统计学意义,与对照组比较,差异无统计学意义。结论:低血糖脑病患者颅脑MRI具有一定的特征性,病变以双侧额顶枕叶多发,具有明显的信号改变。病变部位ADC值的测量有助于患者病情的量化评估。
Objective: To investigate the clinical value of MRI and DWI in the diagnosis of hypoglycemic encephalopathy. Methods: From June 2013 to June 2015, 30 patients with hypoglycemic encephalopathy were selected as observation group and 30 healthy volunteers as control group. All patients underwent MRI and DWI imaging. The characteristics of brain lesions in patients with hypoglycemic encephalopathy were analyzed. The differences of ADC values between the corpus callosum and basal ganglia were compared. Results: The lesion had the highest proportion of bilateral frontal occipital lobe cortical and subcortical lesions with slightly low T1WI signal, slightly high T2WI signal, high T2 FLAIR signal, high DWI signal and so on. Before treatment, the ADC value of corpus callosum and basal ganglia in patients with hypoglycemic encephalopathy was significantly lower than that in the normal control group. After treatment, the ADC value of corpus callosum and basal ganglia in patients with hypoglycemic encephalopathy was significantly higher than that before treatment Statistical significance, compared with the control group, the difference was not statistically significant. Conclusion: MRI of cranial brain in patients with hypoglycemic encephalopathy has certain characteristic. The lesions are frequently occurred in bilateral frontal occipital lobe with obvious signal changes. Measuring the lesion ADC value helps to quantify the patient’s condition.