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目的:探讨小儿骶尾部内胚窦瘤的临床特征及治疗方法。方法:回顾性分析5例骶尾部内胚窦瘤的临床资料并结合文献加以分析。结果:1例患儿未行手术及化疗4个月内死亡,1例术后拒绝化疗6个月内死亡,1例行手术治疗完整切除并行术后化疗6个月后复发;2例术前化疗,行手术完整切除,术后继续化疗,疗程结束至今已达1～2年复查未见复发及转移。结论:小儿骶尾部内胚窦瘤具有典型的临床表现及相应的辅助检查特征,其最佳治疗方法是早期确诊并采用手术切除辅以化疗。
Objective: To investigate the clinical features and treatment of pediatric sacrococcygeal endodermal sinus tumor. Methods: The clinical data of 5 sacrococcygeal endodermal sinus tumors were analyzed retrospectively and combined with the literature. Results: One patient died within 4 months after operation and chemotherapy, one patient died within 6 months after receiving chemotherapy, one patient underwent complete surgical resection and recurred after 6 months of chemotherapy. Chemotherapy, surgery complete resection, postoperative chemotherapy, the end of treatment has reached 1 to 2 years of review no recurrence and metastasis. Conclusion: Pediatric sacrococcygeal endodermal sinus tumor has the typical clinical manifestations and the corresponding auxiliary examination features. The best treatment is pediatric sacrococcygeal endodermal sinus tumor with early diagnosis and surgical resection combined with chemotherapy.