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测定血清中甲状腺激素浓度,可帮助临床诊断甲状腺的功能状态。目前的方法有:测定血清甲状腺素(T_4),三碘甲腺原氨酸(T_3),游离甲状腺素(FT_4)及游离三碘甲腺原氨酸(FT_3)等。FT_3和FT_4虽能较直接反映血中活性激素浓度,但方法较繁琐,不适于常规测定。T_4可作为常规测定,诊断率与蛋白结合碘(PBI)相仿,特异性优于PBI。在患者有甲状腺素结合蛋白(TBP)不正常时,血清T_4就不能如实地反映甲状腺的功能状态。为了克服这个缺点,近年来文献报告从综合T_4和TBP浓度的两种因素进行寻找
Determination of serum thyroid hormone concentration, can help clinical diagnosis of thyroid function status. The current methods are: determination of serum thyroxine (T_4), triiodothyronine (T_3), free thyroxine (FT_4) and free triiodothyronine (FT_3) and so on. Although FT_3 and FT_4 can more directly reflect the concentration of active hormone in blood, the method is cumbersome and not suitable for routine determination. T_4 can be used as a routine test, the diagnostic rate and protein-bound iodine (PBI) similar to the specificity better than the PBI. In patients with thyroid hormone-binding protein (TBP) is not normal, serum T_4 can not faithfully reflect the functional status of the thyroid. In order to overcome this shortcoming, in recent years the literature report has looked for two kinds of factors that synthesize the concentration of T_4 and TBP