目前对急性肾功能衰竭时常采用大剂量速尿疗法。有报告,速尿的利尿效果很显著,能缩短急性肾功能衰竭的少尿期,因而减少对透析的需要以及肾功能得以较快地恢复。一般认为,急性肾功能不全的发病,主要是由于入球小动脉的收缩,而速尿除产生排钠性利尿利用外,还能扩张肾血管以及增加肾的血流量,特别是肾皮质部份的血流量。作者为了进一步探讨这个问题,对56例已确立为急性肾功能衰竭患者进行了大剂量速尿疗法的研究。这些患者的原发病均为外伤或外科手术后,患者随机分组,严格进行对照试验. At present, acute renal failure often use high-dose furosemide therapy. It has been reported that the diuretic effect of furosemide is remarkable, and the oliguria period of acute renal failure can be shortened, thereby reducing the need for dialysis and quicker recovery of renal function. Is generally believed that the incidence of acute renal insufficiency, mainly due to contraction of the arteriole into the ball, and furosemide in addition to produce sodium-based diuretic use, but also to expand the renal blood vessels and increase renal blood flow, especially renal cortical parts Blood flow. In order to further explore this issue, the authors conducted a study of 56 patients who had established acute renal failure with high-dose furosemide. The primary disease in these patients was either traumatic or surgical. Patients were randomly assigned to receive rigorous controlled trials.