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中国药典1985年版法定的抗生素生物检定方法力量反应平行线测定的二剂量或三剂量法,测定结果必须用生物统计方法进行可靠性测验,如果实验可靠再计算效价与平均可信限率。日常抗生素效价测定一般用二剂量法,并且高低剂量之比常为2:1。下面介绍抗生素效价测定(二剂量法)统计计算
Chinese Pharmacopoeia 1985 edition of the antibiotic bioassay method parallel to the determination of force response to the two-dose or three-dose method, the determination of the results must be biometrically reliable method for testing, if the experiment re-calculate the effective price and the average credible rate limit. Daily antibiotic titer is generally used two doses, and the ratio of high and low dose often 2: 1. The following describes the determination of antibiotic potency (two dose method) statistical calculations