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目的验证重症监护室环境清洁消毒标准化干预在预防目标性多重耐药菌(MDRO)感染中的作用。方法选择APIC风险评估模型,筛选出目标性MDRO,用模拟现场实验验证清洁消毒湿巾对目标性多重耐药菌清除效果,并采用前后对照的干预研究,比较干预前后多重耐药菌感染率变化趋势,评价干预效果。结果风险评估显示,MRSA、CRE、VRE、MDR-AB和MDR-PA是该医院的重点监测菌;模拟现场研究显示,清洁消毒湿巾可有效杀灭目标监测菌;趋势性检验显示,经过清洁消毒标准化干预后,MDRO总体感染率、MDRO医院感染率及MDRO定植率均呈现显著下降趋势。结论环境清洁标准化干预措施能够显著降低重症监护室MDRO感染。
Objective To verify the role of standardization of environmental sanitation and disinfection in intensive care unit in preventing MDRO infection. Methods The model of APIC risk assessment was selected and the target MDROs were screened out. Simulated field experiments were conducted to verify the effectiveness of cleaning disinfectant wipes on targeted multidrug-resistant bacteria. Interventions before and after the intervention were used to compare the infection rates of multidrug-resistant bacteria Trend, evaluate the effect of intervention. Results The risk assessment showed that MRSA, CRE, VRE, MDR-AB and MDR-PA were the main monitoring bacteria in this hospital. Simulated field studies showed that the disinfectant wipes effectively killed the target bacteria. The trend test showed that after cleaning After disinfection standardization intervention, MDRO overall infection rate, MDRO hospital infection rate and MDRO colonization rate showed a significant downward trend. Conclusion Environmental clean standardized interventions can significantly reduce MDRO infection in intensive care units.