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端粒组成了真核染色体的末瑞,它由重复排列的六核苷酸5’-TTAGGG-3’组成,它能保护染色体末端免遭核酸外切酶和连接酶的破坏,预防DNA损伤检查DNA点(check point)的活化并抵制线性
The telomeres compose the terminal ray of the eukaryotic chromosome. It consists of a repeating array of hexanucleotides, 5’-TTAGGG-3’, which protects the ends of chromosomes from exonuclease and ligase destruction and prevents DNA damage. Activation of DNA checkpoints and resistance to linearity