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目的探讨125Ⅰ粒子永久组织间植入治疗脊柱转移性骨肿瘤的初步应用体会。方法对16例脊柱转移性骨肿瘤的患者在手术中将放射性粒子125Ⅰ沿椎弓根植入椎骨及其淋巴回流路径。结果本组16例患者随访6-18个月,平均8.4月,均未死亡,亦未发生肿瘤扩散,未出现放射并发症。结论本方法操作简便、使用安全、近期未出现放射性粒子植入后相关并发症,对一些预计有高危复发可能性的脊柱转移性骨肿瘤,是一种好的治疗方法。
Objective To investigate the preliminary application of 125 Ⅰ seed implantation in the treatment of spinal metastatic bone tumor. Methods Sixteen patients with metastatic bone tumors of the spine were implanted 125I radioactive particles along the pedicle into the vertebrae and their lymphatic flow pathways during operation. Results The group of 16 patients were followed up for 6-18 months, an average of 8.4 months, no deaths, no tumor spread, no radiation complications. Conclusion The method is simple, safe to use and has no recent complications after implantation of radioactive particles. It is a good treatment for some patients with metastatic spine bone tumors that are expected to have a high risk of recurrence.