The effect of iron metabolism on anxiety disorder

来源 :转化神经科学电子杂志(英文) | 被引量 : 0次 | 上传用户:wangking88
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Anxiety disorder is one of the most common emotional disorders, but its pathogenesis re-mains unclear. Research has shown that iron deficiency is more common in people with emotional disorders and that these disorders can improve after taking iron supple-ments. Many factors can cause anxiety disorders, includ-ing external stress, genetic factors, impaired neurodevel-opment, and abnormal monoamine metabolism. Studies have shown that abnormal monoamine metabolism and impaired neurodevelopment can contribute to the severity of emotional disorders. The synthesis of serotonin (5-HT) and dopamine (DA) require iron as a cofactor in the syn-thesis of monoamine metabolism, and the release of epi-nephrine (E) was potentially associated with labile iron in plasma. At the same time, iron is also directly involved in myelin synthesis as a cofactor in neural development. Therefore, iron maybe involved some of the main causes of the onset of anxiety disorders.
其他文献
目的 比较股骨近端髓内钉(PFNA)与动力髋螺钉(DHS)治疗Seinsheimer V型股骨粗隆下骨折合并肌少症手术的疗效.方法 回顾性分析2016年1月至2018年12月南京医科大学附属江宁医院骨科收治手术的Seinsheimer V型股骨粗隆下骨折合并肌少症患者52例.根据握力及骨骼肌指数(SMI)诊断肌少症.根据手术方式的不同分为PFNA组(28例)和DHS组(24例).比较两组患者年龄、性别、受伤至手术时间、SMI值、切口长度、手术时间、术中出血量、透视次数,围手术期输血量、下肢完全负重时间、术
目的 通过Meta分析评价髋关节表面置换与全髋关节置换治疗小于60岁中年终末期髋关节疾病患者的临床疗效和安全性.方法 检索2010年10月至2020年10月已发表的关于髋关节表面置换与全髋关节置换的临床对照研究.所检索的数据库包括Pubmed、Embase、Cochrane图书馆、万方数据库、中国知网等.中文检索的关键词为表面置换、全髋置换;英文检索的关键词为hip resur-facing,total hip replacement,total hip arthroplasty.提取数据后,采用Revi
自身炎症性疾病(AIDs)是一组因基因突变致其编码蛋白改变、固有免疫失调,最终导致机体出现全身或器官炎症反应的疾病。AIDs是一组罕见的风湿性疾病,为提高临床医生对AIDs的认识与诊治水平,中华医学会风湿病学分会在借鉴目前国内外经验和指南的基础上,制定了本规范,总结了几种主要AIDs的临床表现,并规范了AIDs的诊断思路和方法。“,”Autoinflammatory diseases (AIDs) are a group of disorders characterized by dysfunction
期刊
The main pathological feature of Alz-heimer\'s disease (AD) is the extracellular deposition of β-amyloid (Aβ) in the brain, which forms insoluble Aβ plaques, and tau protein hyperphosphorylation in neu-rons, which forms intracellular fibrillary tangles.
Radiation therapy is an important part of the comprehensive treatment of brain tumors and one of the most effective treatment methods. However, brain inju-ry is a serious complication. In regards to long-term brain injury caused by radiation therapy, cogn
决奈达隆是Ⅲ类抗心律失常药物,一种脱碘的苯并呋喃衍生物,其抗心律失常作用机制与胺碘酮类似,但不良反应明显减少。决奈达隆主要用于阵发性或持续性心房颤动(房颤)/心房扑动(房扑)患者的节律控制,减少房颤/房扑的复发,并降低再住院风险。不建议决奈达隆用于长程持续性房颤或永久性房颤,以及射血分数减低的房扑或房颤患者。在治疗过程中应该规律监测心电图、电解质和肝肾功能,并注意与其他药物的相互作用。“,”Dronedarone, a class Ⅲ antiarrhythmic drug, is a deiodinat
Cerebrovascular disease is a disease with high morbidity, disability and mortality rates, which seri-ously affects the daily life of patients and is a heavy burden on families and society. Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI)
期刊
Ischemic stroke is a leading cause of death and disability. Despite extensive research, treatment for ischemic stroke is limited to thrombolytic therapy and symptom management. Identifying and testing new therapeutic targets is therefore critical for futu