瘢痕疙瘩的发病机制一直未完全揭示，至今仍无一个令人十分满意的治疗方案。由于患者个体之间的差异性，以及不同治疗方案之间的优势和局限性，致使不同治疗方案的选择对瘢痕疙瘩的治疗和预后产生较大的影响。目前，瘢痕疙瘩的治疗方法主要有药物、物理、手术和心理疗法等。除了传统的治疗方法外，A 型肉毒素、他克莫司、心理干预等也是近年来新兴的治疗热点。现就国外、国内瘢痕疙瘩的临床治疗方法分类，以供临床参考。“,”Currently,the onset mechanism of keloid is not fully elucidated,so far there is no satis-factory therapeutic regimen yet.In addition,due to the heterogeneity in patients coupled with the differ-entiation of advantage and limitation among various therapies,the selection of different protocols has a great impact on the treatment and prognosis of keloids.The mainstream therapies for keloid are medica-tion,physiotherapy, surgery, and psychotherapy.Except for the traditional therapies, there are some other novel emerging approaches such as creotoxin A,tacrolimus and psychological interference.Here is to make a review of the clinical therapies of keloids in China and overseas field, to provide reference for the clinical practice .