核糖核苷酸还原酶抑制剂ｔｒｉｍｉｄｏｘ酶是代谢的关键物质，因而在寻找治疗包括癌症等与不正常代谢有关的疾病的新药过程中，研究重点转向了酶抑制剂。后来发现，一度用于癌症的辅助治疗的羟基脲（ｈｙ－ｄｒｏｘｙｕｒｅａ）是核糖核苷酸还原酶的弱抑制剂。而核糖核苷... Ribonucleotide reductase inhibitors trimidox enzymes are key metabolites of metabolism, and therefore in the search for new drugs, including cancer and other diseases associated with abnormal metabolism, the focus of the study turned to enzyme inhibitors. It was later found that hy-droxyurea, a once adjuvant therapy for cancer, is a weak inhibitor of ribonucleotide reductase. While ribonucleosides ...