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目的:明确芳香开窍方药调控血脑屏障的意义和研究进展。方法:通过中国知网及相关搜索引擎检索近20年有关芳香开窍方药治疗缺血性脑疾病及其作用机理方面的文章,以药物、脑缺血及血脑屏障为关键词检索文献共355篇,用芳香开窍、血脑屏障等关键词对文献进行筛选,对筛选后文献进行阅读,最后应用文献30篇并对其研究结果进行综述,结果发现芳香开窍方药发挥治疗脑缺血性疾病的作用主要是集中在对血脑屏障的通透和双向调控方面。结论:脑缺血可引起血脑屏障通透性发生改变,回医善用香药治疗脑血管疾病,芳香开窍回医回药调控血脑屏障通透性可对脑缺血神经细胞损伤发挥保护作用。
OBJECTIVE: To clarify the significance and research progress of Aromatic Resuscitation Prescription for Regulating Blood-Brain Barrier. Methods: The articles about Aromatic Resuscitation Prescription for the treatment of ischemic brain diseases and its mechanism of action were retrieved by CNKI and related search engines for nearly 20 years. A total of 355 articles were searched from the key words of drugs, cerebral ischemia and blood-brain barrier , The use of aromatic resuscitation, blood-brain barrier and other key words on the screening of the literature screening of the literature after reading, and finally the application of literature 30 and its findings were reviewed and found that Aromatic Resuscitation Prescriptions play a role in the treatment of cerebral ischemic disease Mainly focused on the permeability of the blood-brain barrier and two-way regulation. Conclusion: Cerebral ischemia can cause changes in the permeability of the blood-brain barrier. It can be used as medicine to cure cerebral vascular diseases. Aromatic resuscitation drugs can regulate the permeability of the blood-brain barrier and protect neuronal cells from cerebral ischemia. effect.