氨基比林代谢清除率(MCR)曾被认为是肝内药物氧化酶系统活性的一有用指标。虽然在肝病患者证明氨基比林体内半衰期或MCR与肝微粒体内细胞色素P450含量和药物氧化酶活性之间具有相关性,但在正常人的研究结果却不一致,其原因包括受检的人数太少和肝穿刺活检所取肝组织太少,限制了酶测定的种类。 Aminopyrine Metabolic Clearance (MCR) has been considered a useful indicator of the activity of the intrahepatic drug oxidase system. Although there is a correlation between the half-life of aminopyrine and the cytochrome P450 content and drug oxidase activity of liver microsomes in patients with liver disease, the findings in normal individuals are not consistent because the number of subjects tested is too small And liver biopsy taken too little liver tissue, limiting the type of enzyme assay.