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许多动物研究已表明,抗坏血酸缺乏可引致各种药物的新陈代谢降低;如果给予患坏血病的动物维生素6～10天,则降低之药物酶活性能够恢复到正常水平。作者报告一例抗坏血酸血浆浓度低的躁郁症患者,其抗坏血酸与盐酸氟奋乃静之间可能有的相互作
Many animal studies have shown that ascorbate deficiency can lead to a reduction in the metabolism of various drugs; if the animals suffering from scurvy are given vitamins for 6 to 10 days, the reduced enzyme activity can be restored to normal levels. The authors report an example of a possible association between ascorbic acid and fluphenazine hydrochloride in patients with bipolar disorder with low ascorbate plasma concentrations