论文部分内容阅读
目的:观察小儿消积止咳口服液联合常规西药治疗咳嗽变异型哮喘的疗效。方法:选取140例咳嗽变异型哮喘饮食积滞、痰热蕴肺证患儿作为研究对象,并随机分入观察组和对照组,每组70例。对照组采用硫酸沙丁胺醇雾化溶液联合吸入用布地奈德混悬液氧雾化吸入治疗,观察组在对照组治疗基础上加用小儿消积止咳口服液进行治疗。观察比较2组患儿的治愈时间、药物不良反应发生情况和1年内复发情况。结果:观察组治愈时间较对照组缩短,差异有统计学意义(P<0.01)。观察组复发次数少于对照组,复发时间短于对照组,差异均有统计学意义(P<0.05,P<0.01)。观察组不良反应发生率为1.47%,对照组不良反应发生率为4.48%,2组比较,差异无统计学意义(P>0.05)。结论:应用小儿消积止咳口服液联合西药治疗可以缩短咳嗽变异型哮喘患儿的治愈时间,同时降低复发率,且无明显不良反应,是一种较为安全有效的治疗方法。
Objective: To observe the curative effect of Xiaoji Xiaoji Zhike Oral Liquid and conventional western medicine on cough variant asthma. Methods: A total of 140 children with cough variant asthma were enrolled in this study. The children with phlegm - heat syndrome were selected and randomly divided into observation group and control group, with 70 cases in each group. The control group was treated with salbutamol sulphate nebulization solution combined with inhalation of budesonide suspension aerosolized inhalation. The observation group was treated with Xiaoer Xiaoji Zhike Oral Liquid on the basis of the control group. Two groups of children were observed and compared the healing time, the incidence of adverse drug reactions and recurrence within 1 year. Results: The cure time in the observation group was shorter than that in the control group, with significant difference (P <0.01). The number of recurrence in the observation group was less than that in the control group, and the recurrence time was shorter than that in the control group (P <0.05, P <0.01). The incidence of adverse reactions in the observation group was 1.47%, and the incidence of adverse reactions in the control group was 4.48%. There was no significant difference between the two groups (P> 0.05). Conclusion: The application of Xiaoji Xiaoji Zhike Oral Liquid combined with Western medicine can shorten the cure time of children with cough variant asthma, reduce the recurrence rate and have no obvious adverse reactions, which is a safe and effective treatment.