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目的监测并分析百白破疫苗的安全性和疑似预防接种异常反应(AEFI)发生特征,评价AEFI监测系统运转情况。方法对内蒙古2009-2011年百白破疫苗接种后发生并报告的预防接种异常反应进行调查分析。结果全自治区报告AEFI病例351例,一般反应病例332例,占94.59%;异常反应病例18例,占5.13%;待定1例。接种疫苗后24h内监测到AEFI病例302例,占86.04%。结论百白破疫苗安全性较好,AEFI监测系统灵敏度需进一步提高。
Objective To monitor and analyze the safety of diphtheriae vaccine and the characteristics of suspected immunization abnormalities (AEFI), and evaluate the operation of AEFI monitoring system. Methods An investigation was made on the abnormalities of immunization reported in Inner Mongolia during 2009-2011 after Baibabuai vaccination. Results 351 cases of AEFI cases were reported in the whole autonomous region, 332 were general reaction cases, accounting for 94.59%; 18 cases were abnormal reaction cases, accounting for 5.13%; 1 case was pending treatment. During the 24 hours after vaccination, 302 AEFI cases were detected, accounting for 86.04%. Conclusion Baipi broken vaccine is safe and the sensitivity of AEFI monitoring system needs to be further improved.