Ⅲ度烧伤面积超过90%的患者救治是烧伤治疗的最高难点,其病程长,并发症多而凶险,病死率极高[1]。由于烧伤创面坏死组织是引起全身内皮免疫系统改变,高代谢,过度炎症反应和皮肤屏障功能受损等系列变化的根本原因[2,3],因此正确的处理烧伤创面,尽早去除坏死组织,封闭修复创面非常重要。为此,笔者总结从1977～2008治愈的13例Ⅲ度烧伤面积>90%极其危重的患者有关情况报告如下。 Third degree burn area of ​​more than 90% of patients treated is the highest treatment of burns, the long course of its complications and dangerous, extremely high mortality [1]. As the necrotic tissue of burn wounds is the root cause of a series of changes such as systemic immune system changes, hypermetabolism, excessive inflammatory reaction and impaired skin barrier function [2, 3], the burn wounds are treated properly, necrotic tissues are removed as soon as possible Repair the wound is very important. To this end, the author summarizes from 1977 to 2008 cured 13 cases of Ⅲ degree burn area> 90% of patients in extremely critical condition are reported as follows.