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目的:比较围拔管期应用两种剂量枸橼酸咖啡因在早产儿(胎龄<30周)拔管中的利弊。设计:采用多中心、随机、双盲临床试验。机构:选用澳洲4个3级新生儿单位。患者:胎龄<30周的早产儿,通气时间超过48h。干预:围拔管期给予两种剂量的枸橼酸咖啡因[20
OBJECTIVE: To compare the pros and cons of extubation in extubation of two doses of citrulline citrate in preterm infants (gestational age <30 weeks). Design: Multi-center, randomized, double-blind clinical trial. Organization: Choose Australia 4 3 newborn units. Patients: Premature infants <30 weeks gestational age with ventilatory time> 48 h. Intervention: Peritubation was given two doses of citrate caffeine [20