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早期宫颈癌预后良好。主要治疗手段为放疗和/或手术切除,然而少数患者尽管为癌症早期且经过适度治疗仍旧死亡。为鉴别此类高危患者,Sten-dahl 等引入宫颈癌恶性肿瘤分级系统,该组织病理分级涉及8个检验参数,对预测同期宫颈癌患者中的高危者有一定价值。本文观察各病理参数与DNA型之间是否相关。作者选择 Uppsala 大学医院和 Orebro 医学中心的159例鳞状宫颈细胞癌患者,依 FIGO 标准分级,取自肿瘤的活组织行组织病理检查和流式细胞计数分析,并与20例正常宫颈组织进行对照。分析结果表明:72例为 IB 期,55例为Ⅱ期,2例为Ⅲ期,10例为Ⅳ期。其中分化良好者5例,中等分化72例,低分化82例。DNA 值为1.7C～8.0C。57例为围二倍体(Peridiploid)(1.8～2.2C),
Early cervical cancer prognosis is good. The main treatment is radiotherapy and / or surgical resection, however a small number of patients are still dead early and with moderate treatment of cancer. To identify such high-risk patients, Sten-dahl et al introduced a cervical cancer malignancy grading system that involved eight test parameters in the pathological grading and was of value in predicting high-risk patients with cervical cancer over the same period. This article observes the correlation between the pathological parameters and DNA type. The authors selected 159 patients with squamous cell carcinoma of the cervix at Uppsala University Hospital and Orebro Medical Center, who were graded according to the FIGO standard. Tissues from the tumor were examined by histopathology and flow cytometry, and compared with 20 normal cervical tissues . The results of the analysis showed that 72 cases were stage IB, 55 cases were stage II, 2 cases were stage III and 10 cases were stage IV. Among them, 5 were well-differentiated, 72 moderately differentiated, and 82 poorly differentiated. DNA value of 1.7C ~ 8.0C. 57 cases were peridiploid (1.8 ~ 2.2C),