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目的 探讨胃嗜酸性肉芽肿 (GEG)的可能的发病原因。方法 回顾分析 48例GEG的临床表现及病理特点 ;采用改良Giemsa法检测幽门螺杆菌 (Hp)。结果 GEG有明显的性别差异 ,术前误诊率高 ,68 8%病变组织中有淋巴滤泡 ,Hp阳性检出率 69 6% ,周围血中 11例嗜酸性白细胞增高。结论 Hp感染、性激素水平及过敏反应有可能与GEG发病有关
Objective To investigate the possible pathogenesis of gastric eosinophilic granuloma (GEG). Methods The clinical manifestations and pathological features of 48 cases of GEG were retrospectively analyzed. Helicobacter pylori (Hp) was detected by modified Giemsa method. Results There was a significant gender difference in GEG. The preoperative misdiagnosis rate was high. Lymphoid follicles were present in 68.8% of the diseased tissues. The positive rate of Hp was 69.6% and the number of eosinophils in 11 peripheral blood was increased. Conclusion Hp infection, sex hormone levels and allergic reactions may be related to the pathogenesis of GEG