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目的:为了寻找术前鉴别皮质醇腺瘤和腺癌的指标及观察术后疗效,我们对收治的36例该类病人进行回顾性分析。腺瘤病人30例,腺癌6例,分别收集两组病人的一般资料,肿瘤大小,生化结果,术后情况进行比较。结果:腺瘤和腺癌均以女性和左侧肾上腺多发,腺瘤患病年龄明显小于腺癌,腺瘤直径也明显小于后者。30例腺瘤病人1例死于术后低血糖症,余29例术后激素替代时间17.2±9.1个月,无复发。腺癌病人均于术后5年内死亡。结论:病人的年龄和肿瘤的大小可能作为术前鉴别皮质醇腺瘤和腺癌的一项指标,腺瘤病人预后良好,腺癌病人则预后差。
Objective: In order to find the preoperative identification of cortisol adenocarcinoma and adenocarcinoma and to observe the curative effect, we retrospectively analyzed 36 cases of such patients. 30 cases of adenoma and 6 cases of adenocarcinoma. The general data, tumor size, biochemical results and postoperative condition of the two groups were collected respectively. Results: Both adenomas and adenocarcinomas were predominant in women and the left adrenal glands. The age of adenomas was significantly less than that of adenocarcinomas, and the diameter of adenomas was also significantly smaller than that of adenocarcinomas. One patient died of postoperative hypoglycemia in 30 patients with adenoma, and the remaining 29 patients had postoperative hormone replacement time of 17.2 ± 9.1 months with no recurrence. Patients with adenocarcinoma died within 5 years after surgery. Conclusion: The age of the patient and the size of the tumor may be used as an indicator of preoperative cortisol adenocarcinoma and adenocarcinoma. The prognosis of adenoma patients is good, and the prognosis of patients with adenocarcinoma is poor.