介绍了8-羟基喹啉微型化合成方法 ,即在浓硫酸作用下,使甘油脱水生成丙烯醛,并使邻氨基酚与丙烯醛的加成物脱水成环,硝基酚氧化下,合成了8-羟基喹啉。实验结果表明,在超声波辅助下,以浓硫酸作为脱水剂,硝基酚作为氧化剂,合成8-羟基喹啉达到反应终点时间仅为18 min,收率为87.5%,有效地提高了实验效率。 This paper introduced the miniaturization method of 8-hydroxyquinoline. Under the action of concentrated sulfuric acid, the dehydration of glycerol to acrolein and the adduct of o-aminophenol and acrolein were dehydrated to form a ring. Under the oxidation of nitrophenol, 8-hydroxyquinoline. The experimental results showed that with the aid of ultrasonic wave, with concentrated sulfuric acid as dehydrating agent and nitrophenol as oxidant, the reaction time of 8-hydroxyquinoline reached 18 min, the yield was 87.5%, which effectively improved the experimental efficiency.