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目的：研究丹参对增生性瘢痕的影响。方法：采用同体动态对照，以自制丹参药膏和纯基质分别外涂于增生性瘢痕３个月，测定瘢痕组织厚度的变化及瘢痕组织中羟脯氨酸含量。结果：①用药组瘢痕厚度较用药前明显减少（Ｐ＜０．０１），而对照组瘢痕组织厚度无显著改变（Ｐ＞０．０５）。②用药组瘢痕组织羟脯氨酸含量明显低于对照组（Ｐ＜０．０１）。结论：证明丹参能抑制增生性瘢痕胶原沉积，使瘢痕组织明显变薄，对增生性瘢痕有肯定的治疗作用。
Objective: To study the effects of salvia miltiorrhiza on hypertrophic scars. Methods: Using the same body dynamic control, self-made Salvia miltiorrhiza ointment and pure matrix were applied to hypertrophic scar for 3 months respectively. Changes in scar tissue thickness and hydroxyproline content in scar tissue were determined. RESULTS: 1 The scar thickness in the medication group was significantly lower than before the medication (P<0.01), while the thickness of the scar tissue in the control group was not significantly changed (P>0.05). The content of hydroxyproline in the scar tissue of the medication group was significantly lower than that of the control group (P<0.01). Conclusion: It is proved that Salvia miltiorrhiza can inhibit the collagen deposition of hypertrophic scar, make the scar tissue obviously thin, and have a certain therapeutic effect on hypertrophic scar.